![]() ![]() ![]() The most common side effects of acetaminophen are rash, nausea and headache. If you have any type of liver problems, take other medications that can damage the liver, or drink three or more alcoholic drinks per day, you may not be able to take even OTC acetaminophen or must be followed very closely by your doctor. What are the possible side effects of acetaminophen?Īcetaminophen is generally very safe depending on your age and other illnesses that might affect whether you can take acetaminophen. Also, make sure your doctor knows everything you are taking for your pain, even OTC drugs or supplements. Talk to your doctor about your options for managing your pain. Since taking acetaminophen regularly for pain can rarely cause side effects, particularly at higher doses, talk to your doctor about the best way to ease your pain.Įven OTC pills can have serious side effects, especially if you take them often. If you overdo physical activity on certain days and ache afterward, acetaminophen may be helpful for relieving your short-term pain. You may just need to take it on days when your pain feels worse than normal. You may not have to take acetaminophen long term. Or, your rheumatologist may prescribe a stronger dose of acetaminophen for your pain if needed. You may need to take acetaminophen for joint pain or stiffness from time to time. Severe liver injury can lead to liver failure, liver transplant, and death. The greatest risk for severe liver injury happens when people take more than the prescribed dose of acetaminophen, take more than one acetaminophen-containing product at the same time, or drink alcohol while taking acetaminophen. The FDA also asked drug makers to stop producing combination prescription medications with more than 325 milligrams of acetaminophen (which typically contain acetaminophen plus an opioid painkiller such as codeine). The move was one of a series of actions the FDA took to limit high-dose use of the drug. In 2014 the Food and Drug Administration (FDA) began asking doctors to stop prescribing combination medications that contain more than 325 milligrams of acetaminophen per pill because of concerns about liver damage. The dose for extended release caplets is 1300 mg every 8 hours. The dose for adults is 325 mg every 4 hours or 500 mg every 8 hours when using immediate release formulations. It reduces fever by acting on the heat-regulating center of the brain, causing the center to lower your body’s temperature. Acetaminophen relieves pain by elevating the pain threshold, meaning it requires a greater amount of pain to develop before a person feels it. It may reduce the brains’ production of prostaglandins, which are chemicals that cause inflammation and swelling. The exact mechanism of action of acetaminophen is not known. The most common side effects, though rare, are rash, nausea, and headache.Īcetaminophen belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers). It is generally safe to use for minor fares of pain and typically does not have side effects, though large amounts taken over a long period of time can potentially cause liver damage. It is sold over the counter, but your doctor may also write you a prescription for acetaminophen. Acetaminophen is sold under the brand name Tylenol® and is typically used to treat pain and reduce fever. ![]()
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